Yes, you can manipulate Impossible film.
The PX70 film is not as easy to manipulate as the original polaroid SX70 film. When you want to draw on the PX70 film, you will need to heat up the image with a hairdryer first, and you will need to draw with a lot more pressure.
PX silvershade and colorshade films need to get lifted within half an hour/an hour after shooting. The older the image, the more difficult it is to lift it.